K41498
Cat. No. :YN321849
CAS No. :434938-41-7
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5mg
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Product Name: | K41498 |
CAS NO.: | 434938-41-7 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 3632.20 |
Molecular Formula: | C₁₆₂H₂₇₆N₄₈O₄₆ |
SMILES: | [{D-Phe}-HLLRK-{Nle}-IEIEKQEKEKQQAANNRLLLDTI-NH2] |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | K41498 is a potent and highly selectiveCRF2 receptorantagonist with Ki values of 0.66nM, 0.62nM and 425nM for human CRF2α, CRF2β and CRF1receptors respectively. K41498 is an analogues of antisauvagine-30 (aSvg-30), inhibits sauvagine-stimulated cAMP accumulation in hCRF2α- and hCRF2β-expressing cells. K41498 can be used for hypotension study. |
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