YN320420 VUF11207 fumarate 1785665-61-3

VUF11207 fumarate (Compound 29) is aCXCR7agonist and a high-potencyCXCR7(pKiof 8.1) lig and that induces recruitment ofβ-arrestin2(pEC50of 8.8) and subsequent internalization (pEC50of 7.9) ofCXCR7.

YN320097 CXCR2-IN-1 1873376-49-8

CXCR2-IN-1 is a central nervous system penetrantCXCR2antagonists with apIC50 of 9.3.

YN320459 LIT-927 2172879-52-4

LIT-927 is a novel neutraligand of CXCL12 with Ki value of 267 nM for inhibition of Texas red-labeled CXCL12 (CXCL12-TR) binding. It shows high selectivity toward CXCL12 vs other chemokines also involved in a...

YN320349 CXCR7 modulator 1 2231812-31-8

CXCR7 modulator 1 (compound 25) is a potent and orally bioavailable peptoid hybridCXCR7modulator, with a Ki of 9nM.

YN321275 Mavorixafor trihydrochloride 2309699-17-8

Mavorixafor trihydrochloride (AMD-070 trihydrochloride) is a potent, selective and orally availableCXCR4antagonist, with an IC50 value of 13nM against CXCR4125I-SDF binding, and also inhibits the replication of T-tro...

YN321755 Corydalmine

Corydalmine (L-Corydalmine), an alkaloid isolated from roots ofCorydalis Chaerophylla, inhibits spore germination of some plant pathogenic as well as saprophytic fungi. Corydalmine acts as an oral analgesic agent, exhibiting potent an...