Sodium formononetin-3'-sulfonate
Cat. No. :YN330234
CAS No. :949021-68-5
Product Name: | Sodium formononetin-3'-sulfonate |
CAS NO.: | 949021-68-5 |
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Molecular Weight: | 370.31 |
Molecular Formula: | C₁₆H₁₁NaO₇S |
SMILES: | OC1=CC=C(C2=C1)C(C(C3=CC(S(=O)(O[Na])=O)=C(OC)C=C3)=CO2)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Sodium formononetin-3'-sulfonate (Sul-F) is a water-sol. derivate of formononetin. Research results showed that treatment with Sul-F significantly prevented the elevation of ST-segment level, decreased the contents of creatine kinase-MB, lactate dehydrogenase, alanine aminotransferase and cardiac troponin T in serum and reduced the myocardium necrosis scores. These findings indicate that Sul-F has a protective potential against myocardial infarction injury. A possible mechanism for the protective effect is the elevated expression of endogenous antioxidant defense enzymes degraded lipid peroxidn. products and improved energy metab. of cardiac mitochondrial, thus attenuating cardiocyte apoptosis. Other reaearch results showed that sodium formononetin-3'-sulfonate not only had favorable water, solubility but also had good lipid-lowering and liver-protection activities. |
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