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Nepicastat

Cat. No. :YN1570004

  • CAS No. :173997-05-2

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    • Product Name:Nepicastat
      CAS NO.:173997-05-2
      Chemical Name:
      Synonyms:
      Molecular Weight:295.35
      Molecular Formula:C₁₄H₁₅F₂N₃S
      SMILES:FC1=CC(F)=C2CC[C@@H](CC2=C1)N3C(CN)=CNC3=S
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:Nepicastat (SYN117) is a selective, potent, and orally active inhibitor ofdopamine-beta-hydroxylase. Nepicastat (SYN117) produces concentration-dependent inhibition of bovine (IC50=8.5nM) and human (IC50=9nM) dopamine-beta-hydroxylase. Nepicastat (SYN117) can cross the blood-brain barrier (BBB) .
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