IK1 inhibitor PA-6
Cat. No. :YN360278
CAS No. :500715-03-7
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order@ubiochem.com| Product Name: | IK1 inhibitor PA-6 |
| CAS NO.: | 500715-03-7 |
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| Molecular Weight: | 492.61 |
| Molecular Formula: | C₃₁H₃₂N₄O₂ |
| SMILES: | N=C(C1=CC=CC=C1)NC2=CC=C(OCCCCCOC3=CC=C(NC(C4=CC=CC=C4)=N)C=C3)C=C2 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | IK1 inhibitor PA-6 (PA-6), a pentamidine analogue, is a selective and potentIK1(KIR2.x ion-channel-carried inward rectifier current) inhibitor, with IC50 values of 12-15nM for human and mouse KIR2.x currents. IK1 inhibitor PA-6 (PA-6) elevates KIR2.1 protein expression and induces intracellular KIR2.1 accumulation. IK1 inhibitor PA-6 (PA-6) has the potential to treat atrial fibrillation and arrhythmia . |
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