Avatrombopag hydrochloride
Cat. No. :YN330245
CAS No. :570403-17-7
86-020-82000279
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order@ubiochem.com| Product Name: | Avatrombopag hydrochloride |
| CAS NO.: | 570403-17-7 |
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| Molecular Weight: | 686.12 |
| Molecular Formula: | C₂₉H₃₅Cl₃N₆O₃S₂ |
| SMILES: | O=C(C1CCN(C2=NC=C(C(NC3=NC(C4=CC(Cl)=CS4)=C(N5CCN(C6CCCCC6)CC5)S3)=O)C=C2Cl)CC1)O.Cl |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Avatrombopag (AKR-501) hydrochloride is an orally active, nonpeptidethrombopoietin (TPO) receptoragonist (EC50=3.3nM). Avatrombopag hydrochloride mimics the biological activities of TPO. Avatrombopag hydrochloride increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag hydrochloride is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A . |
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