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Sanggenon C

Cat. No. :YN410113

  • CAS No. :80651-76-9

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    • Product Name:Sanggenon C
      CAS NO.:80651-76-9
      Chemical Name:
      Synonyms:
      Molecular Weight:708.71
      Molecular Formula:C₄₀H₃₆O₁₂
      SMILES:C/C(C)=C/C[C@](C1=CC=C(O)C=C1O2)(OC3=CC(O)=C([C@@H](C=C(C)C[C@@H]4C(C=CC(O)=C5)=C5O)[C@@H]4C(C(C=CC(O)=C6)=C6O)=O)C(O)=C3C7=O)[C@]27O
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:Sanggenon C is a flavanone Diels-Alder adduct compound, which is isolated from the root bark ofMorus cathayana. Sanggenon C exerts protective effects against cardiac hypertrophy and fibrosis via suppression of thecalcineurin/NFAT2pathway. Sanggenon C inhibits inducible nitric oxide synthase expression in RAW264.7 cells, and tumor necrosis factor-α-stimulated cell adhesion and vascular cell adhesion molecule-1 expression, by suppressingNF-κBactivity. Sanggenon C possesses antioxidant, anti-inflammatory activities and inhibits Pancreatic lipase (PL) with the an IC50 of 3.00 μM.
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