Finerenone
Cat. No. :YN370505
CAS No. :1050477-31-0
Product Name: | Finerenone |
CAS NO.: | 1050477-31-0 |
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Molecular Weight: | 378.42 |
Molecular Formula: | C₂₁H₂₂N₄O₃ |
SMILES: | O=C(C1=C(C)NC2=C(C(OCC)=NC=C2C)[C@@H]1C3=CC=C(C#N)C=C3OC)N |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Finerenone (BAY 94-8862) is a third-generation, selective, and orally available nonsteroidalmineralocorticoid receptor (MR)antagonist (IC50=18nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), and rogen receptor (AR), and progesterone receptor (>500-fold). Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease. |
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