RWJ-56110 dihydrochloride
Cat. No. :YN320371
CAS No. :2387505-58-8
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order@ubiochem.com| Product Name: | RWJ-56110 dihydrochloride |
| CAS NO.: | 2387505-58-8 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 863.65 |
| Molecular Formula: | C₄₁H₄₅Cl₄F₂N₇O₃ |
| SMILES: | O=C(N[C@H](C(NCC1=CC=CC=C1)=O)CCN)[C@@H](NC(NC2=CC3=C(C=C2)C(CN4CCCC4)=CN3CC5=C(Cl)C=CC=C5Cl)=O)CC6=CC=C(F)C(F)=C6.[H]Cl.[H]Cl |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor ofPAR-1activation and internalization (bindingIC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. RWJ-56110 dihydrochloride inhibits the aggregation of human platelets induced by both SFLLRN-NH2 (IC50=0.16μM) and thrombin (IC50=0.34μM), quite selective relative to U46619 (HY-108566). RWJ-56110 dihydrochloride blocks angiogenesis and blocks the formation of new vessels in vivo. RWJ-56110 dihydrochloride induces cellapoptosis. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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