Rosuvastatin D3
Cat. No. :YN360628
CAS No. :1133429-16-9
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order@ubiochem.com| Product Name: | Rosuvastatin D3 |
| CAS NO.: | 1133429-16-9 |
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| Molecular Weight: | 484.56 |
| Molecular Formula: | C₂₂H₂₅D₃FN₃O₆S |
| SMILES: | FC(C=C1)=CC=C1C2=NC(N(C([2H])([2H])[2H])S(=O)(C)=O)=NC(C(C)C)=C2/C=C/[C@@H](O)C[C@@H](O)CC(O)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Rosuvastatin D3 (ZD 4522 D3) is a deuterium labeled Rosuvastatin. Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC50 of 11nM. Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals. |
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