Zoniporide hydrochloride hydrate
Cat. No. :YN360151
CAS No. :863406-85-3
Product Name: | Zoniporide hydrochloride hydrate |
CAS NO.: | 863406-85-3 |
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Molecular Weight: | 374.82 |
Molecular Formula: | C₁₇H₁₉ClN₆O₂ |
SMILES: | O=C(C1=C(C2CC2)N(C3=C4C=CC=NC4=CC=C3)N=C1)NC(N)=N.[H]Cl.[H]O[H] |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Zoniporide (CP-597396) hydrochloride hydrate is a potent and selective inhibitor ofsodium-hydrogen exchanger type 1 (NHE-1). Zoniporide hydrochloride hydrate inhibits human NHE-1 (IC50=14nM), and has >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride hydrate potently inhibits ex vivo NHE-1-dependent swelling of human platelets (IC50=59nM). |
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