Setanaxib
Cat. No. :YN370966
CAS No. :1218942-37-0
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5mg
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Product Name: | Setanaxib |
CAS NO.: | 1218942-37-0 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 394.85 |
Molecular Formula: | C₂₁H₁₉ClN₄O₂ |
SMILES: | O=C1N(C2=CC=CC=C2Cl)NC(C1=C(C3=CC=CC(N(C)C)=C3)N4C)=CC4=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | GKT137831 is a potent, dual NADPH oxidase NOX1/NOX4 inhibitor with Ki of 110 nM and 140 nM, respectivelyl ~10-fold selectivity towards NOX1, 4 and 5 over NOX2, does not inhibit XO or scavange ROS/RNS. |
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