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DMX-5804

Cat. No. :YN350072

  • CAS No. :2306178-56-1

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    • Product Name:DMX-5804
      CAS NO.:2306178-56-1
      Chemical Name:
      Synonyms:
      Molecular Weight:361.39
      Molecular Formula:C₂₁H₁₉N₃O₃
      SMILES:O=C1NC=NC2=C1C(C3=CC=C(OCCOC)C=C3)=CN2C4=CC=CC=C4
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:DMX-5804 is a potent, orally active and selective inhibitor of Mitogen-activated protein kinase kinase kinase kinase-4 (MAP4K4) with IC50 of 3 nM for human MAP4K4. DMX-5804 is more potent on human MAP4K4 with pIC50 of 8.55 than MINK1/MAP4K6 and TNIK/MAP4K7 with pIC50 of 8.18 and 7.96, respectively.
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