20-HETE
Cat. No. :YN330315
CAS No. :79551-86-3
86-020-82000279
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order@ubiochem.com| Product Name: | 20-HETE |
| CAS NO.: | 79551-86-3 |
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| Molecular Weight: | 320.47 |
| Molecular Formula: | C₂₀H₃₂O₃ |
| SMILES: | O=C(O)CCC/C=CC/C=CC/C=CC/C=CCCCCCO |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | 20-HETE (20-hydroxy Arachidonic Acid) is a CYP450 metabolite and a potent vasoconstrictor. 20-HETE is an endogenous inhibitor of the large-conductanceCa2+-activated K+channelin renal arterioles. 20-HETE constricts smooth muscles, stimulates smooth muscle proliferation and migration. 20-HETE increasesNADPH oxidase,ROS, and NF-κBactivity. 20-HETE also inhibits endothelialNO synthase and inhibitsapoptosisof pulmonary artery smooth muscle cells. |
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