HET0016
Cat. No. :YN371003
CAS No. :339068-25-6
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5mg
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25mg
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Product Name: | HET0016 |
CAS NO.: | 339068-25-6 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 206.28 |
Molecular Formula: | C₁₂H₁₈N₂O |
SMILES: | CCCCC1=CC=C(C(C)=C1)/N=C/NO |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | HET0016 is a potent and selective20-hydroxyeicosatetraenoic acid (20-HETE)synthase inhibitor, with IC50 values of 17.7nM, 12.1nM and 20.6nM for recombinant CYP4A1-, CYP4A2- and CYP4A3-catalyzed 20-HETE synthesis, respectively. HET0016 also is a selectiveCYP450inhibitor, which has been shown to inhibit angiogenesis and tumor growth. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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