GSK180736A
Cat. No. :YN450128
CAS No. :817194-38-0
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5mg
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Product Name: | GSK180736A |
CAS NO.: | 817194-38-0 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 365.36 |
Molecular Formula: | C₁₉H₁₆FN₅O₂ |
SMILES: | CC(N1)=C(C(NC2=CC=C(NN=C3)C3=C2)=O)C(C4=CC=C(F)C=C4)NC1=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | GSK180736A, developed as a Rho-associated, coiled-coil-containing protein kinase inhibitor, binds to GRK2(G protein-coupled receptor kinase 2) with logIC50 pf -6.6 (logIC50 -4.0 for GRK5 and >-3 for GRK1) ≥400-fold selective for GRK2 over both GRK1 and GRK5. |
IC50&Target: | |
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Clinical Trial: | |
Solvent & Solubility: | |
References: |
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