Zatebradine hydrochloride
Cat. No. :YN360423
CAS No. :91940-87-3
Product Name: | Zatebradine hydrochloride |
CAS NO.: | 91940-87-3 |
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Molecular Weight: | 493.04 |
Molecular Formula: | C₂₆H₃₇ClN₂O₅ |
SMILES: | O=C1N(CCCN(CCC2=CC=C(OC)C(OC)=C2)C)CCC3=CC(OC)=C(OC)C=C3C1.Cl |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Zatebradine (UL-FS-49 (free base)) is a potent inhibitor ofhyperpolarization-activated cyclic nucleotide-gated (HCN) channelswith an IC50 values 1.96 µM. Zatebradine blocks the slow inward current through humanHCN1,HCN2,HCN3 and HCN4 channels, with IC50 values of 1.83 µM, 2.21 µM, 1.90 µM and 1.88 µM, respectively. |
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