Aprocitentan
Cat. No. :YN321048
CAS No. :1103522-45-7
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order@ubiochem.com| Product Name: | Aprocitentan |
| CAS NO.: | 1103522-45-7 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 546.19 |
| Molecular Formula: | C₁₆H₁₄Br₂N₆O₄S |
| SMILES: | O=S(N)(NC1=NC=NC(OCCOC2=NC=C(Br)C=N2)=C1C3=CC=C(Br)C=C3)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Aprocitentan (ACT-132577) is the major and pharmacologically active metabolite of Macitentan. Aprocitentan is dualETA/ETBantagonist with IC50s of 3.4nM and 987nM, and pA2valus of 6.7 and 5.5, respectively. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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