TRAF-STOP inhibitor 6877002
Cat. No. :YN410015
CAS No. :433249-94-6
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order@ubiochem.com| Product Name: | TRAF-STOP inhibitor 6877002 |
| CAS NO.: | 433249-94-6 |
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| Molecular Weight: | 251.32 |
| Molecular Formula: | C₁₇H₁₇NO |
| SMILES: | O=C(C1=CC=CC=C1)/C=C/NC2=C(C=CC(C)=C2)C |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | TRAF-STOP inhibitor 6877002, is a selective inhibitor ofCD40-TRAF6interaction, compound VII, shows inhibition ofNF-κBactivation in RAW cells, extracted from patent WO2014033122A1. TRAF-STOP 6877002 prevents the progression of established atherosclerosis in mice, reduces leukocyte recruitment and reduces macrophage activation; reduces macrophage proliferation in atherosclerotic plaques. |
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