VU0134992 hydrochloride
Cat. No. :YN360324
CAS No. :1052515-91-9
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Product Name: | VU0134992 hydrochloride |
CAS NO.: | 1052515-91-9 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 447.84 |
Molecular Formula: | C₂₀H₃₂BrClN₂O₂ |
SMILES: | O=C(NC1CC(C)(C)NC(C)(C)C1)COC2=CC=C(C(C)C)C=C2Br.[H]Cl |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | VU0134992 hydrochloride is the first subtype-preferring, orally active and selectiveKir4.1 potassium channelpore blocker, with an IC50 of 0.97 µM. VU0134992 hydrochloride is 9-fold selective for homomeric Kir4.1 over Kir4.1/5.1 concatemeric channels (IC50=9 µM) at -120 mV. |
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