SC99
Cat. No. :YN340102
CAS No. :882290-02-0
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Product Name: | SC99 |
CAS NO.: | 882290-02-0 |
Chemical Name: | |
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Molecular Weight: | 336.15 |
Molecular Formula: | C₁₅H₈Cl₂FN₃O |
SMILES: | N#C/C(C(C1=CC=C(Cl)C=C1)=O)=NNC2=CC=C(F)C(Cl)=C2 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | SC99 is an orally active, selectiveSTAT3inhibitor targeting JAK2-STAT3 pathway. SC99 docks into the ATP-binding pocket of JAK2. SC99 inhibits phosphorylation of JAK2 and STAT3 with no effects on the other kinases associated with STAT3 signaling. SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activities . |
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