NF449 octasodium
Cat. No. :YN360277
CAS No. :627034-85-9
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order@ubiochem.com| Product Name: | NF449 octasodium |
| CAS NO.: | 627034-85-9 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 1505.09 |
| Molecular Formula: | C₄₁H₂₄N₆Na₈O₂₉S₈ |
| SMILES: | O=C(NC1=CC(C(NC2=CC=C(S(=O)(O[Na])=O)C=C2S(=O)(O[Na])=O)=O)=CC(C(NC3=CC=C(S(=O)(O[Na])=O)C=C3S(=O)(O[Na])=O)=O)=C1)NC4=CC(C(NC5=CC=C(S(=O)(O[Na])=O)C=C5S(=O)(O[Na])=O)=O)=CC(C(NC6=CC=C(S(=O)(O[Na])=O)C=C6S(=O)(O[Na])=O)=O)=C4 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | NF449 octasodium is a highly potentP2X1receptorantagonist, with IC50s of 0.28, 0.69, and 120nM for rP2X1, rP2X1+5, P2X2+3, respectively. NF449 octasodium is a Gsα-selectiveG Proteinantagonist. NF449 octasodium suppresses the rate of GTP[γS] binding to Gsα-s, inhibits the stimulation of adenylyl cyclase activity, and blocks the coupling of β-adrenergic receptors to Gs. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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