Deoxyshikonin
Cat. No. :YN251584
CAS No. :43043-74-9
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Product Name: | Deoxyshikonin |
CAS NO.: | 43043-74-9 |
Chemical Name: | |
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Molecular Weight: | 272.30 |
Molecular Formula: | C₁₆H₁₆O₄ |
SMILES: | O=C1C(CC/C=C(C)/C)=CC(C2=C1C(O)=CC=C2O)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Deoxyshikonin is isolated fromLithospermum erythrorhizonSieb with antitumor activity. Deoxyshikonin increases the expression ofVEGF-C and VEGF-AmRNA in HMVEC-dLy, promotes HIF-1α and HIF-1β subunit interaction and binds to specific DNA sequences targeted byHIF, indicates a prolymphangiogenesis as well as a proangiogenesis effect in vitro. Deoxyshikonin shows significant synergic antimicrobial activity againstS. pneumonia(MIC=17 μg/mL), also shows significantly inhibitory activities against MRSA. |
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