RP-64477
Cat. No. :YN372394
CAS No. :135239-65-5
86-020-82000279
sales@ubiochem.com
order@ubiochem.com| Product Name: | RP-64477 |
| CAS NO.: | 135239-65-5 |
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| Molecular Weight: | 498.72 |
| Molecular Formula: | C₂₉H₄₂N₂O₃S |
| SMILES: | O=C(NCCCC)C1=CC=C(SC)C(NC(C2=CC=C(OCCCCCCCCCC)C=C2)=O)=C1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | RP-64477 is a potent inhibitor of the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT). RP-64477 inhibits ACAT activity with IC50 of 113 nM, 503 nM, and 180 nM in human intestinal (CaCo-2), hepatic (HepG2) and monocytic (THP-1) cell assays, respectively. |
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