Marein
Cat. No. :YN420317
CAS No. :535-96-6
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order@ubiochem.com| Product Name: | Marein |
| CAS NO.: | 535-96-6 |
| Chemical Name: | |
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| Molecular Weight: | 450.39 |
| Molecular Formula: | C₂₁H₂₂O₁₁ |
| SMILES: | O=C(C1=CC=C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)C(O)=C1O)/C=C/C3=CC=C(O)C(O)=C3 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Marein has the neuroprotective effect due to a reduction of damage to mitochondria function and activation of theAMPK signal pathway. Marein improves insulin resistance induced by high glucose in HepG2 cells through CaMKK/AMPK/GLUT1 to promote glucose uptake, through IRS/Akt/GSK-3β to increase glycogen synthesis, and through Akt/FoxO1 to decrease gluconeogenesis. Marein is a HDA Cinhibitor with an IC50 of 100 µM. Marein has beneficial antioxidative, antihypertensive, antihyperlipidemic and antidiabetic effects . |
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