RO2959 monohydrochloride
Cat. No. :YN330135
CAS No. :2309172-44-7
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order@ubiochem.com| Product Name: | RO2959 monohydrochloride |
| CAS NO.: | 2309172-44-7 |
| Chemical Name: | |
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| Molecular Weight: | 463.93 |
| Molecular Formula: | C₂₁H₂₀ClF₂N₅OS |
| SMILES: | O=C(NC1=NC=C(C2=C(C)CCN(C3=NC=C(C)S3)C2)N=C1)C4=C(F)C=CC=C4F.[H]Cl |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | RO2959 monohydrochloride is a potent and selectiveCRAC channelinhibitor with an IC50 of 402nM. RO2959 monohydrochloride is a potent blocker ofstore operated calcium entry (SOCE)mediated byOrai1/Stim1 channelswith an IC50 of 25nM. RO2959 monohydrochloride is also a potent inhibitor ofhuman IL-2production, and potently blocks T cell receptor triggered gene expression and T cell functional pathways. |
| IC50&Target: | |
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