RO2959 hydrochloride
Cat. No. :YN330134
CAS No. :1219927-22-6
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5mg
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25mg
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Product Name: | RO2959 hydrochloride |
CAS NO.: | 1219927-22-6 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 无Molecular Weight |
Molecular Formula: | C₂₁H₁₉F₂N₅OS.xHCl |
SMILES: | O=C(NC1=NC=C(C2=C(C)CCN(C3=NC=C(C)S3)C2)N=C1)C4=C(F)C=CC=C4F.[xHCl] |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | RO2959 hydrochloride is a potent and selectiveCRAC channelinhibitor with an IC50 of 402nM. RO2959 hydrochloride is a potent blocker ofstore operated calcium entry (SOCE)mediated byOrai1/Stim1 channelswith an IC50 of 25nM. RO2959 hydrochloride is also a potent inhibitor ofhuman IL-2production, and potently blocks T cell receptor triggered gene expression and T cell functional pathways. |
IC50&Target: | |
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References: |
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