INDY
Cat. No. :YN440112
CAS No. :1169755-45-6
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order@ubiochem.com| Product Name: | INDY |
| CAS NO.: | 1169755-45-6 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 235.30 |
| Molecular Formula: | C₁₂H₁₃NO₂S |
| SMILES: | CC(/C=C1SC2=CC=C(O)C=C2N1CC)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | INDY is a potent and ATP-competitiveDyrk1A and Dyrk1Binhibitor with IC50s of 0.24μM and 0.23μM, respectively. INDY binds in the ATP pocket of the enzyme and has aKivalue of 0.18μM for Dyrk1A. INDY sharply reduces the self-renewal capacity of normal and tumorigenic cells in primary Glioblastoma (GBM) cell lines and neural progenitor cells. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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