7α,25-Dihydroxycholesterol
Cat. No. :YN320469
CAS No. :64907-22-8
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5mg
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Product Name: | 7α,25-Dihydroxycholesterol |
CAS NO.: | 64907-22-8 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 418.65 |
Molecular Formula: | C₂₇H₄₆O₃ |
SMILES: | C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)(O)C)([H])[C@@]3([H])[C@]([C@@]4(C(C[C@@H](O)CC4)=C[C@H]3O)C)([H])CC1 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | 7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous lig and of the orphan GPCR receptorEBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly potent at activating EBI2 (EC50=140 pM;Kd=450 pM). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells. |
IC50&Target: | |
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References: |
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