YN373290 Aloe-emodin-8-O-β-D-glucop... 33037-46-6

Aloe-emodin-8-O-β-D-glucopyranoside, a compound isolated fromSaussrurea lappa, is a moderate inhibitor ofhuman protein tyrosine phosphatase 1B (hPTP1B)with an IC50 of 26.6μM.

YN321613 Amitraz 33089-61-1

Amitraz is a triazapentadiene, an α2 adrenergic agonist and a member of the amidine chemical family. It is a non-systemic acaricide and insecticide.

YN320273 AH 6809 33458-93-4

AH 6809 is an antagonist ofEP and DP receptor, with a Ki of 1217, 1150, 1597, and 1415nM for the clonedhuman EP1,EP2,EP3-III, and DP receptorrespectively, and with a Ki of 350nM formouse EP2receptor .

YN321805 Substance P 33507-63-0

Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P isneurokinin 1 receptor(NK1-receptor,NK1R).

YN482510 Silychristin 33889-69-9

Silychristin is an abundant flavonolignan present in the fruits ofSilybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporterMCT8, and elicits a strong inhibition of T3 uptak...

YN321735 (20S)-Protopanaxatriol 34080-08-5

(20S)-Protopanaxatriol(g-PPT), a neuroprotective metabolite of ginsenoside, protopanaxatriol (g-PPT), is a functional ligand for both GR and ERbeta and could modulate endothelial cell functions through the glucocorticoid recepto...

YN321976 Angiotensin II (5-8), human 34233-50-6

Angiotensin II (5-8), human is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II. Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and ...

YN321727 Ginsenoside Ro 34367-04-9

Ginsenoside Ro, one of the high-abundance saponins in ginseng, is widely used as a dietary supplement and has many health-promoting effects.

YN321148 Acebutolol hydrochloride 34381-68-5

Acebutolol is a β-adrenergic receptors antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias.

YN321397 Ketotifen fumarate 34580-14-8

Ketotifen Fumarate is a fumaric acid salt of ketotifen which is a H1-antihistamine and mast cell stabilizer.

YN321562 Urapidil 34661-75-1

Urapidil is an antihypertensive drug acting as an α1 adrenoreceptor antagonist and a 5-HT1A agonist.

YN321002 Metiamide 34839-70-8

Metiamide (SK&F 92058) is a histamine H2-receptor antagonist developed from another H2 antagonist, burimamide.

YN484368 Norgestimate 35189-28-7

Norgestimate, a synthetic progesterone analog, is an orally activeprogestinwith highly selective progestational activity  and  minimal  and rogenicity. Norgestimate is used for an oral contraceptive.

YN480925 Carboprost 35700-23-3

Carboprost is a form of prostaglandin (a hormone-like substance that occurs naturally in the body). Prostaglandins help to control functions in the body such as blood pressure and muscle contractions.

YN321320 Talipexole dihydrochloride 36085-73-1

Talipexole dihydrochloride (B-HT 920 dihydrochloride) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist and 5-HT3 receptor antagonist, which displays antiParkinsonian activity.

YN321058 Metipranolol hydrochloride 36592-77-5

Metipranolol hydrochloride is a non-selectiveβ adrenergic receptorblocking agent.

YN320171 Pargolol hydrochloride 36902-82-6

Pargolol hydrochloride is aβ adrenergic receptorantagonist.

YN321163 Carbetocin 37025-55-1

Carbetocin (Lonactene; Duratocin) is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth; an agonist at peripheral oxytocin receptors.

YN482042 Bentiromide 37106-97-1

Bentiromide is a peptide that is broken down in the pancreas by chymotrypsin. The bentiromide test is an excellent means of confirming the diagnosis of pancreatic exocrine insufficiency by outpatient test of chymotrypsin function.

YN372951 Zaprinast 37762-06-4

Zaprinast (M&B 22948) is an inhibitor of cGMP-selectivePhosphodiesterases(PDEs). Zaprinast is aG protein-coupled receptor (GPR) 35agonist which activates rat GPR35 strongly and activates human GPR35 moderately. Zapri...