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PF-04457845

Cat. No. :YN372200

  • CAS No. :1020315-31-4

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    • Products Infomation
    • Biological Activity
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    • Product Name:PF-04457845
      CAS NO.:1020315-31-4
      Chemical Name:
      Synonyms:PF-4457845
      Molecular Weight:455.43
      Molecular Formula:C₂₃H₂₀F₃N₅O₂
      SMILES:O=C(NC1=NN=CC=C1)N(CC/2)CCC2=CC3=CC=CC(OC4=NC=C(C(F)(F)F)C=C4)=C3
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:PF-04457845 is a potent, favorable selective inhibitor of Fatty acid amide hydrolase (FAAH) with IC50 of 7.2 nM and 7.4 nM for hFAAH and rFAAH, respectively. PF-04457845 covalently modifies the active-site serine nucleophile of FAAH with exquisite selectivity relative to other members of the serine hydrolase superfamily.
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