PF-04457845
Cat. No. :YN372200
CAS No. :1020315-31-4
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Product Name: | PF-04457845 |
CAS NO.: | 1020315-31-4 |
Chemical Name: | |
Synonyms: | PF-4457845 |
Molecular Weight: | 455.43 |
Molecular Formula: | C₂₃H₂₀F₃N₅O₂ |
SMILES: | O=C(NC1=NN=CC=C1)N(CC/2)CCC2=CC3=CC=CC(OC4=NC=C(C(F)(F)F)C=C4)=C3 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | PF-04457845 is a potent, favorable selective inhibitor of Fatty acid amide hydrolase (FAAH) with IC50 of 7.2 nM and 7.4 nM for hFAAH and rFAAH, respectively. PF-04457845 covalently modifies the active-site serine nucleophile of FAAH with exquisite selectivity relative to other members of the serine hydrolase superfamily. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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