DC260126
Cat. No. :YN320206
CAS No. :346692-04-4
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5mg
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Product Name: | DC260126 |
CAS NO.: | 346692-04-4 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 307.38 |
Molecular Formula: | C₁₆H₁₈FNO₂S |
SMILES: | O=S(C1=CC=C(F)C=C1)(NC2=CC=C(CCCC)C=C2)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | DC260126 is a potent antagonist ofGPR40 (FFAR1). DC260126 dose-dependently inhibits GPR40-mediated Ca2+elevations stimulated by linoleic acid, oleic acid, palmitoleic acid and lauric acid (IC50: 6.28, 5.96, 7.07, 4.58μM, respectively). DC260126 could protect MIN6 β cells from palmitate-induced ER stress and apoptosis. |
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