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DC260126

Cat. No. :YN320206

  • CAS No. :346692-04-4

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    • Products Infomation
    • Biological Activity
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    • Product Name:DC260126
      CAS NO.:346692-04-4
      Chemical Name:
      Synonyms:
      Molecular Weight:307.38
      Molecular Formula:C₁₆H₁₈FNO₂S
      SMILES:O=S(C1=CC=C(F)C=C1)(NC2=CC=C(CCCC)C=C2)=O
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:DC260126 is a potent antagonist ofGPR40 (FFAR1). DC260126 dose-dependently inhibits GPR40-mediated Ca2+elevations stimulated by linoleic acid, oleic acid, palmitoleic acid and lauric acid (IC50: 6.28, 5.96, 7.07, 4.58μM, respectively). DC260126 could protect MIN6 β cells from palmitate-induced ER stress and apoptosis.
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