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Glucocorticoid Receptor

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN320773 21-Acetoxypregna-1,4,9(11),16... 37413-91-5

    21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione is anintermediateof delta 9,11 steroids synthesis, for example, VamoroloneĀ (HY-109017). The delta 9,11 steroids are modifications of glucocorticoids and hasanti-inflammatorypropertie...

  • YN321625 Amcinonide 51022-69-6

    Amcinonide (Cyclocort, CL-34699) is an inhibitor of nitric oxide (NO) release from activated microglia with IC50 of 3.38 nM.

  • YN320760 Budesonide 51333-22-3

    Budesonide is a glucocorticoid steroid for the treatment of asthma, non-infectious rhinitis.

  • YN321356 Alclometasone 67452-97-5

    Alclometasone (7a-Chloro-16a-methyl prednisolone) is aglucocorticoid and inhibits the release of pro-inflammatory mediators from leukocytes. Alclometasone can be used to relieve corticosteroid-responsive dermatoses, including atopicĀ de...

  • YN321396 Fluticasone (propionate) 80474-14-2

    Fluticasone Propionate is a synthetic glucocorticoid, used to treat non-allergic and allergic rhinitis.

  • YN321119 Loteprednol Etabonate 82034-46-6

    Loteprednol etabonate is a potent glucocorticoid receptor agonist, used in treatment of inflammation of the eye due to allergies.

  • YN322059 Amebucort 83625-35-8

    Amebucort is a synthetic glucocorticoid corticosteroid, may used for the research of inflammatory disorders.

  • YN320788 Mometasone furoate 83919-23-7

    Mometasone Furoate is a glucocorticoid receptor agonist, used topically to reduce inflammation of the skin or in the airways.

  • YN320786 Mifepristone 84371-65-3

    Mifepristone is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively.

  • YN321546 Ciclesonide 126544-47-6

    Ciclesonide is a glucocorticoid used to treat obstructive airway diseases.

  • YN320441 Desisobutyryl-ciclesonide 161115-59-9

    Desisobutyryl-ciclesonide is the active metabolite of Ciclesonide. Desisobutyryl-ciclesonide has affinity for theglucocorticoid receptor.

  • YN321018 AL 082D06 256925-03-8

    AL082D06 is a nonsteroidal glucocorticoid receptor (GR) antagonist with no detectable binding affinity for the highly related receptors for mineralocorticoids, androgens, estrogens, and progestins.

  • YN320948 Fluticasone furoate 397864-44-7

    Fluticasone furoate is an inhaled corticosteroid/long-acting beta-agonist combination with a prolonged bronchodilator duration of action. It is used for the treatment of non-allergic and allergic rhinitis administered by a nasal spray.

  • YN320922 (S)-Mapracorat 887375-15-7

    (S)-Mapracorat is a selective and less active glucocorticoid receptor agonist.

  • YN320921 Mapracorat 887375-26-0

    Mapracorat is a novel non-steroidal selectiveglucocorticoid receptoragonist.

  • YN320756 Betamethasone hydrochloride 956901-32-9

    Betamethasone hydrochloride is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activities. Betamethasone hydrochloride accelerates fetal lung maturation and induces gene expression and apoptosis.

  • YN321019 Cort108297 1018679-79-2

    Cort108297 is a specificglucocorticoid receptor(GR) antagonist. Cort108297 has a high affinity for GRs with a Ki of 0.45nM.

  • YN320354 AZD5423 1034148-04-3

    AZD5423 is an inhaled, potent, selective, and non-steroidalglucocorticoid receptor (GR)modulator (SGRM). AZD5423 effectively reduces allergen-induced responses in subjects with mild allergic asthma.

  • YN320468 AZD2906 1034148-15-6

    AZD2906 is a selectiveglucocorticoid receptor (GR)agonist, increases micronucleated immature erythrocytes in the bone marrow of rats. AZD2906 shows IC50s of 2.2, 0.3, 41.6 and 7.5nM at GR in human, rat PBMC and human, r...

  • YN320002 Budesonide impurity C 1040085-99-1

    Budesonide impurity C is an impurity of Budesonide. Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist.

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