YN250657 GSK2838232 1443460-91-0

GSK2838232 inhibit HIV reverse transcriptase activity across a broad panel of HIV-1 isolates, extracted from patent WO/2013090664A1, compound51.

YN250010 9-Propenyladenine 1446486-33-4

9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral drug known as nucleotide analogue reverse transcriptase inhibitors, which block reverse transcriptase, a crucial virus enzyme in H...

YN250011 (Z)-9-Propenyladenine 1464851-21-5

(Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral drug known as nucleotide analogue reverse transcriptase (NtART) inhibitor, which blocks reverse transcriptase, a crucial v...

YN250811 BRD3308 1550053-02-5

BRD3308 is a potant and highly selective inhibitor of HDAC3 with IC50 of 54 nM, 1.26 μM and 1.34 μM for HDAC3, HDAC1 and HDAC2, respectively. BRD3308 activates HIV-1 transcription. BRD3308 suppresse...

YN251809 Peptide T TFA 1610056-01-3

Peptide T (TFA) is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a lig and for theCD4receptor and prevents binding ofHIVto the CD4 receptor.

YN250417 HIV-1 inhibitor-3 1612841-22-1

HIV-1 inhibitor-3 is aHIVinfection inhibitor extracted from patent US2018360927.

YN250207 Lenacapavir 2189684-44-2

Lenacapavir (GS-6207) is aHIV-1 capsidinhibitor. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells. Lenacapavir displays a mean EC50 of 50 pM (20-160 pM) against 23 HIV-1 clinical isolates from ...

YN250389 ZL0580 2377151-10-3

ZL0580, a structurally close analog of ZL0590, induces epigenetic suppression ofHIVvia selectively binding to BD1 domain ofBRD4. ZL0580 induces HIV suppression by inhibiting Tat transactivation and transcription elongati...