Suramin sodium salt
Cat. No. :YN310339
CAS No. :129-46-4
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50mg
$ 300.00
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order@ubiochem.com| Product Name: | Suramin sodium salt |
| CAS NO.: | 129-46-4 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 1429.17 |
| Molecular Formula: | C₅₁H₃₄N₆Na₆O₂₃S₆ |
| SMILES: | O=C(NC1=CC(C(NC2=CC(C(NC3=CC=C(S(=O)(O[Na])=O)C4=CC(S(=O)(O[Na])=O)=CC(S(=O)(O[Na])=O)=C34)=O)=CC=C2C)=O)=CC=C1)NC5=CC(C(NC6=CC(C(NC7=CC=C(S(=O)(O[Na])=O)C8=CC(S(=O)(O[Na])=O)=CC(S(=O)(O[Na])=O)=C78)=O)=CC=C6C)=O)=CC=C5 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Suramin sodium salt (Suramin hexasodium salt) is a reversible and competitiveprotein-tyrosine phosphatases (PTPases)inhibitor. Suramin sodium salt is a potent inhibitor ofsirtuins: SirT1 (IC50=297nM), SirT2 (IC50=1.15μM), and SirT5 (IC50=22μM). Suramin sodium salt is a competitive inhibitor of reverse transcriptase (DNA topoisomerase II:IC50=5μM).. Suramin sodium salt efficiently inhibitsIP5K and is anantiparasitic, anti-neoplastic and anti-angiogenic agent..[7]. |
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