SB 203580 hydrochloride
Cat. No. :YN350024
CAS No. :869185-85-3
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order@ubiochem.com| Product Name: | SB 203580 hydrochloride |
| CAS NO.: | 869185-85-3 |
| Chemical Name: | |
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| Molecular Weight: | 413.90 |
| Molecular Formula: | C₂₁H₁₇ClFN₃OS |
| SMILES: | O=S(C1=CC=C(C2=NC(C3=CC=C(F)C=C3)=C(C4=CC=NC=C4)N2)C=C1)C.[H]Cl |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | SB 203580 hydrochloride (RWJ 64809 hydrochloride) is a selective and ATP-competitivep38 MAPKinhibitor with IC50s of 50nM and 500nM forSAPK2a/p38 and SAPK2b/p38β2, respectively. SB 203580 hydrochloride inhibits LCK, GSK3β and PKBα with IC50s of 100-500-fold higher than that for SAPK2a/p38. SB 203580 hydrochloride is anautophagy and mitophagyactivator. |
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