YQ128
Cat. No. :YN330233
CAS No. :2454246-18-3
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5mg
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Product Name: | YQ128 |
CAS NO.: | 2454246-18-3 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 545.11 |
Molecular Formula: | C₂₇H₂₉ClN₂O₄S₂ |
SMILES: | O=S(C1=CC=C(CCN(CC2=C(C=CC(Cl)=C2)OCCC)C(CC3=CSC=C3)=O)C=C1)(NCC#C)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | YQ128 is a potent and selective second-generationNLRP3 (NOD-like receptor P3) inflammasomeinhibitor with an IC50 of 0.30 µM. YQ128 significantly and selectively suppresses the production ofIL-1β, but not TNF-α, and it can cross the BBB to reach the CNS. YQ128 has anti-inflammatory activity. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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