PRN694
Cat. No. :YN440222
CAS No. :1575818-46-0
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order@ubiochem.com| Product Name: | PRN694 |
| CAS NO.: | 1575818-46-0 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 543.67 |
| Molecular Formula: | C₂₈H₃₅F₂N₅O₂S |
| SMILES: | O=C(C1=CC=C(C(F)F)S1)NC2=NC3=CC(CN[C@@H](C)C(C)(C)C)=CC=C3N2C[C@@H]4N(C(C=C)=O)CCC4 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | PRN694 is an irreversible, highly selective and potent covalentinterleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK)dual inhibitor with IC50s of 0.3nM and 1.4nM, respectively. PRN694 exhibits extended target residence time on ITK and RLK, enabling durable attenuation of effector cellsin vitro and in vivo. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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