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SP600125

Cat. No. :YN350095

  • CAS No. :129-56-6

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    • Products Infomation
    • Biological Activity
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    • Product Name:SP600125
      CAS NO.:129-56-6
      Chemical Name:
      Synonyms:Nsc75890
      Molecular Weight:220.23
      Molecular Formula:C₁₄H₈N₂O
      SMILES:O=C1C2=C3C(NN=C3C4=C1C=CC=C4)=CC=C2
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:SP600125 is a broad-spectrum JNK inhibitor for JNK1, JNK2 and JNK3 with IC50 of 40 nM, 40 nM and 90 nM in cell-free assays, respectively 10-fold greater selectivity against MKK4, 25-fold greater selectivity against MKK3, MKK6, PKB, and PKCα, and 100-fold selectivity against ERK2, p38, Chk1, EGFR etc.
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