SP600125
Cat. No. :YN350095
CAS No. :129-56-6
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5mg
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Product Name: | SP600125 |
CAS NO.: | 129-56-6 |
Chemical Name: | |
Synonyms: | Nsc75890 |
Molecular Weight: | 220.23 |
Molecular Formula: | C₁₄H₈N₂O |
SMILES: | O=C1C2=C3C(NN=C3C4=C1C=CC=C4)=CC=C2 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | SP600125 is a broad-spectrum JNK inhibitor for JNK1, JNK2 and JNK3 with IC50 of 40 nM, 40 nM and 90 nM in cell-free assays, respectively 10-fold greater selectivity against MKK4, 25-fold greater selectivity against MKK3, MKK6, PKB, and PKCα, and 100-fold selectivity against ERK2, p38, Chk1, EGFR etc. |
IC50&Target: | |
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Clinical Trial: | |
Solvent & Solubility: | |
References: |
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