IQ-3
Cat. No. :YN350052
CAS No. :312538-03-7
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5mg
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Product Name: | IQ-3 |
CAS NO.: | 312538-03-7 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 341.32 |
Molecular Formula: | C₂₀H₁₁N₃O₃ |
SMILES: | O=C(O/N=C1C2=C(C3=NC4=CC=CC=C4N=C31)C=CC=C2)C5=CC=CO5 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | IQ 3 is a specific c-Jun N-terminal kinase (JNK) inhibitor with Kd of 66 nM, 240 nM and 290 nM for JNK3, JNK1 and JNK2, respectively. IQ 3 inhibits LPS-induced NF-κB/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 μM. IQ 3 also inhibits TNF-α and IL-6 production in vitro. |
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References: |
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