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APTO-253

Cat. No. :YN350177

  • CAS No. :916151-99-0

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    • Products Infomation
    • Biological Activity
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    • Product Name:APTO-253
      CAS NO.:916151-99-0
      Chemical Name:
      Synonyms:
      Molecular Weight:367.38
      Molecular Formula:C₂₂H₁₄FN₅
      SMILES:CC(N1)=C(C(N2)=NC3=C2C4=CC=CN=C4C5=NC=CC=C53)C6=C1C=CC(F)=C6
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:APTO-253 is a small molecule that inhibitsc-Mycexpression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosisin acute myeloid leukemia cells. APTO-253 mediates anticancer activity through induction of theKrüppel-like factor 4 (KLF4)tumor suppressor.
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