DMX-5804
Cat. No. :YN350072
CAS No. :2306178-56-1
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5mg
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Product Name: | DMX-5804 |
CAS NO.: | 2306178-56-1 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 361.39 |
Molecular Formula: | C₂₁H₁₉N₃O₃ |
SMILES: | O=C1NC=NC2=C1C(C3=CC=C(OCCOC)C=C3)=CN2C4=CC=CC=C4 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | DMX-5804 is a potent, orally active and selective inhibitor of Mitogen-activated protein kinase kinase kinase kinase-4 (MAP4K4) with IC50 of 3 nM for human MAP4K4. DMX-5804 is more potent on human MAP4K4 with pIC50 of 8.55 than MINK1/MAP4K6 and TNIK/MAP4K7 with pIC50 of 8.18 and 7.96, respectively. |
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References: |
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