URMC-099
Cat. No. :YN350115
CAS No. :1229582-33-5
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order@ubiochem.com| Product Name: | URMC-099 |
| CAS NO.: | 1229582-33-5 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 421.54 |
| Molecular Formula: | C₂₇H₂₇N₅ |
| SMILES: | CN(CC1)CCN1CC(C=C2)=CC=C2C3=CN=C4C(C(C5=CC=C(NC=C6)C6=C5)=CN4)=C3 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | URMC-099 is an orally bioavailable, brain penetrant mixed lineage kinase (MLK) inhibitor with IC50 of 19 nM, 42 nM, 14 nM, and 150 nM, for MLK1, MLK2, MLK3, and DLK, respectively, and also inhibits LRRK2 activity with IC50 of 11 nM. |
| IC50&Target: | |
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