Lazabemide hydrochloride
Cat. No. :YN380095
CAS No. :103878-83-7
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Product Name: | Lazabemide hydrochloride |
CAS NO.: | 103878-83-7 |
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Molecular Weight: | 236.10 |
Molecular Formula: | C₈H₁₁Cl₂N₃O |
SMILES: | O=C(C1=NC=C(Cl)C=C1)NCCN.[H]Cl |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Lazabemide hydrochloride (Ro 19-6327 hydrochloride) is a selective, reversible inhibitor ofmonoamine oxidase B (MAO-B)(IC50=0.03μM) but less active for MAO-A (IC50>100μM). Lazabemide inhibits monoamine uptake at high concentrations, the IC50 values are 86μM, 123μM and >500μM for noradrenalin, serotonin and dopamine uptake, respectively. Lazabemide can be used for the research of parkinson and alzheimer′s disease. |
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