Tetrabenazine Racemate
Cat. No. :YN360812
CAS No. :718635-93-9
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order@ubiochem.com| Product Name: | Tetrabenazine Racemate |
| CAS NO.: | 718635-93-9 |
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| Molecular Weight: | 317.42 |
| Molecular Formula: | C₁₉H₂₇NO₃ |
| SMILES: | O=C1C(CC(C)C)CN2CCC3=CC(OC)=C(OC)C=C3C2C1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Tetrabenazine Racemate (Ro 1-9569 Racemate) is a selective and reversible inhibitor of vesicular monoamine transporter-2 (VMAT-2). (1) The reference for administration is 0.25-0.75 mg/kg IP (2) Injections of tetrabenazine into accumbens core also reduced FR5 lever pressing and increased chow intake. (3) Tetrabenazine (Racemate) reduced extracellular DA and altered DARPP-32 signaling in both substance-P- and enkephalin-containing accumbens neurons. (4) Tetrabenazine (Racemate) inhibits locomotor activity and produces hypothermia upon systemic administration in rats and mice. |
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