Bufalin
Cat. No. :YN360944
CAS No. :465-21-4
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order@ubiochem.com| Product Name: | Bufalin |
| CAS NO.: | 465-21-4 |
| Chemical Name: | |
| Synonyms: | BF |
| Molecular Weight: | 386.52 |
| Molecular Formula: | C₂₄H₃₄O₄ |
| SMILES: | O[C@]([C@@](CC[C@@]1([H])[C@@]2(CC[C@H](O)C1)C)([H])[C@]2([H])CC3)(CC[C@@H]4C(C=C5)=COC5=O)[C@]34C |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Bufalin is a potent inhibitor of steroid receptor coactivator SRC-3, SRC-1 and Na+/K+-ATPase. Bufalin binds to the subunit α1, α2 and α3 of Na+/K+-ATPase with Kd of 42.5 nM, 45 nM and 40 nM, respectively. Bufalin is a major digoxin-like immunoreactive component isolated from the Chinese medicine Chan Su with anti-cancer activity. |
| IC50&Target: | |
| In Vitro: | |
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| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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