Facinicline hydrochloride
Cat. No. :YN320351
CAS No. :677305-02-1
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Product Name: | Facinicline hydrochloride |
CAS NO.: | 677305-02-1 |
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Molecular Weight: | 306.79 |
Molecular Formula: | C₁₅H₁₉ClN₄O |
SMILES: | [H]Cl.O=C(C1=NNC2=C1C=CC=C2)N[C@@H]3CN4CCC3CC4 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Facinicline hydrochloride (RG3487 hydrochloride) is an orally activenicotinic α7 receptorpartial agonist, with a Ki of 6nM for α7 human nAChR. Facinicline hydrochloride (RG3487 hydrochloride) improves cognition and sensorimotor gating in rodents. Facinicline hydrochloride (RG3487 hydrochloride) shows high affinity (antagonist) to 5-HT3Rs with a Kivalue of 1.2nM. |
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