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> Products > Inhibitors & Agonists > ADC Related > PROTAC-linker Conjugate for PA

PAC

Cat. No. :YN430062

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    • Products Infomation
    • Biological Activity
    • Reference
    • Product Name:PAC
      CAS NO.:2158322-33-7
      Chemical Name:
      Synonyms:
      Molecular Weight:1674.93
      Molecular Formula:C₉₄H₁₀₇N₁₃O₁₆
      SMILES:CN(C(COCCOCCNC(C1=CC=C(C(N2[C@@H](C)[C@H](NC([C@H](C)NC)=O)C(N(CC3=C(OC)C=CC4=C3C=CC=C4)C5=C2C=C(C#N)C=C5)=O)=O)C=C1)=O)=O)CCOC(C=C6)=CC=C6/C(C7=CC=C(OCC(C=C8)=CC=C8NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN9C(C=CC9=O)=O)=O)=O)=O)C=C7)=C(C%10=CC=CC=C%10)/CC
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:PAC, consists the ADCs linker and PROTACs, conjugated to an antibody. PAC extracts from patent WO2017201449A1, compound LP2. PAC conjugated to an antibody is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab).
      IC50&Target:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
      References:
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