Talmapimod
Cat. No. :YN350040
CAS No. :309913-83-5
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order@ubiochem.com| Product Name: | Talmapimod |
| CAS NO.: | 309913-83-5 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 513.00 |
| Molecular Formula: | C₂₇H₃₀ClFN₄O₃ |
| SMILES: | O=C(N(C)C)C(C1=CN(C)C2=C1C=C(C(N3[C@H](C)CN(CC4=CC=C(F)C=C4)[C@@H](C)C3)=O)C(Cl)=C2)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Talmapimod (SCIO-469) is an orally active, selective, and ATP-competitivep38αinhibitor with an IC50 of 9nM. Talmapimod shows about 10-fold selectivity over p38β, and at least 2000-fold selectivity over a panel of 20 other kinases, including other MAPKs . |
| IC50&Target: | |
| In Vitro: | |
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| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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