Agerafenib
Cat. No. :YN350154
CAS No. :1188910-76-0
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order@ubiochem.com| Product Name: | Agerafenib |
| CAS NO.: | 1188910-76-0 |
| Chemical Name: | |
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| Molecular Weight: | 517.46 |
| Molecular Formula: | C₂₄H₂₂F₃N₅O₅ |
| SMILES: | O=C(NC1=NOC(C(C)(C)C(F)(F)F)=C1)NC2=CC=CC(OC3=C(C=C(OC)C(OC)=C4)C4=NC=N3)=C2 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | CEP-32496 is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret, PDGFRβ and VEGFR2, respectively insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2. Phase 1/2. |
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